The enamine synthesis was from two starting materials were acetylacetone and dibenzoylmethane, the NMR spectrum was clear of enamine from acetylacetone their appearance coupling between nitrogen atom and enolic hydrogen (3JN-H =51 Hz). The NMR spectrum of enamine from dibenzoylmethane didn’t appear any coupling eno-form and keto-form because of the steric hindrance of aromatic ring. The study has involved preparations of two starting materials and two enamine preparations from starting materials as ligands, they are as IUPAC names (Z)-4-aminopent-3-en-2-one, acetyl acetone, 1,3-diphenylpropane-1,3-dione and (Z)-3-amino-1,3-diphenylprop-2-en-1-one.The study also proved the molecular structures of the metal complexes of the acetylacetone, dibenzoylmethane and prepared reagents (enamine), they are eight complexes preparation their tetrahedral and octahedral, all ligands combine with metals as enol form. In this study, also a DFT calculation for some properties of (Z)-4-aminopent-3-en-2-one and (Z)-3-amino-1,3-diphenylprop-2-en-1-one has been carried out. The study scanned charge Mulliken, HOMO and LUMO, dipole moment and total energy of two the synthesis ligands.

Liver is an important organ in the body however, the modern diet pattern including fast and fatty foods, certain medicines etc causes liver tissue damage and is a threat to life. Certain natural spices have protective potentiality on the liver. This narrative review focuses mainly on the clinical evidence of the intervention of spices on liver protective potentiality. Clinical evidences are the most updated, best evidence for effective health care. PubMed was searched using the keywords ‘Botanical name of the spice’ OR ‘extract of spices’ name’ OR ‘common name of the spice’ OR ‘main active ingredient of the spice’ with ‘liver enzymes’ OR ‘liver protector’ OR ‘hepato protector’ OR ‘non – alcoholic fatty liver disease (NAFLD)’ up to 2019 and only English language articles were considered. In this review, Cinnamomum zeylanicum, Curcuma longa, Allium sativum, Zingiber officinale, Nigella sativa and Elettaria cardamomum clinically established their potentiality as liver protectors. Only animal studies were available to show the potentiality for Myristica fragrans, Piper nigrum, Syzygium aromaticum and Coriandrum sativum and hence, they were not included. Review suggests that the daily use of spices should be increased as our ancestors did in the past. Also, the number of human trials should be increased.

Daruparpatadi decoction has been used extensively in Sri-Lanka for treatment of a number of respiratory tract ailments. No studies have examined the bioactive compounds present in this decoction. the aim of the study was to assess and compare the phytochemicals present in the hot aqueous, hexane, ethyl acetate and ethanol extracts of the Decoction of the Daruparpatadi. Hot aqueous, hexane, ethyl acetate and ethanol extracts of the Decoction of the Daruparpatadi were prepared and all the preliminary phytochemical test were done with standard methods. A wide variety of pharmacologically active phytochemical compounds such as higher amount of tannins and phenolic compounds, terpenoids and steroids, flavonoids, cardiac glycosides, carbohydrates, amino acids, anthaquinone glycosides and resins were found in this hot aqueous and ethanol extract of the Daruparpatadi. Alkaloids found higher in the ethanol extract. Saponins were less in all four extracts comparing with the other phytochemicals. The qualitative phyto-compounds of this decoction confirm the use for various ailments such as asthma, phlegmatic fever, colds and tuberculosis by the practitioners. Further, the quantitative analysis of these phyto-compounds will be an interesting area for further study to exploit the other biomedical applications.

In the present paper, we have developed a new methodology and solution procedure for solving stochastic multi-choice bi-level programming problems taking the right hand side parameters of the constraints in both first level and second level as multi-choice parameters but constraints and objective function coefficients in both leaders and followers as exponential random variables with known means. In order to solve the proposed model, equivalent deterministic non-linear bi-level programming models are established by using binary variable transformation technique. Then the models are solved by using KKT approach and obtained the optimal solution. A numerical example is constituted to illustrate the utility of the proposed methodology and solution procedure.

Obesity is a global problem all over the world and the health problems associated with obesity are numerous. Dietary factors are the major modifiable factors by which many of the external influencing factors for the excess weight gain can be minimized. The aim of the study is to explore the dietary factors which influence on the excess weight gain in females. A cross-sectional study was conducted at the National Ayurveda Teaching Hospital, Borella. Data were collected from 247 female participants in a pre-structured questionnaire by interviewing subjects through face to face interview. ANOVA and multiple regression models were used to analyze and predict factors which influence to the obesity. “Dietary amount” variable showed a significant positive relationship with the BMI at the level p < 0.01. This depicts that the amount of food consumed is directly proportional to the BMI. Further, in the present study, excess eating habits and excess consumption of non-vegetarian diet were shown as significant influencing factors to obesity. Also excess consumption of “samba” rice and excess usage of oil were also considered as influencing factors to obesity. Further, another noteworthy observation is that most of the “Kekulu” and “Nadu” rice consumers were overweight, but not obese. When compared to the correlation between additional eating and obesity, the correlation between banana eating and obesity is negligible. Study concluded that implementation and encouragement for healthy eating habits and appropriate intervention to promote physical activity to diminish the increasing percentages of the obesity in the society.

Albizia lebbeck fruit pod (ALFP) was used for the Biosorption of Cu(II) and Ni(II) ions in a batch adsorption set up. The sorption capacity was ALFP was investigated as a function of adsorbent dose, initial metal ion concentration, pH, temperature, agitation time and shaking speed. The adsorption efficiency of metal ion uptake with ALFP increases with adsorbent concentration, temperature and agitation time, decreases with increase in metal ion concentration and shows initial rise followed by a decline with pH and shaking speed. The sorption process was very fast and equilibrium was achieved in 40 min.Equilibrium data fitted well to Freundlich isotherms model. Batch adsorption models, based on assumption of first-order, pseudo-second order, Elovich equation and Weber and Morris intra-particle diffusion model were utilized to identify the rate and kinetics of sorption of copper and nickel onto ALFP. Pseudo-second order model was found to best fit the kinetic data. FTIR and SEM were used to study the surface characteristics of ALFP. Thermodynamic parameters such as〖 ∆H〗^0, 〖∆S〗^0 and 〖∆G〗^0 were calculated describing adsorption process to be endothermic and spontaneous. The study supported the use of ALFP as a cheap, effective and eco-friendly alternative for the treatment of Cu(II) and Ni(II) containing.

The article outlines the European integration preconditions of Ukraine in the implementation of legal and judicial reform. It is emphasized on the existence of clear requirements to the countries - members of the European Union on the quality of legal and judicial organizational support. The current stage of judicial reform is also described. The theoretical content of the judicial reform, its success criteria and the obstacles to its progress are revealed

In this present work, the modern adjusted (G?G)-expansion method has been utilized to produce numerous and various traveling wave solutions according to the zoomeron and the phi-4 equations by assist two ordinary differential equations from second order .In addition, we will obtain different functions via our solutions including exponential, trigonometric, hyperbolic, and rational functions. Furthermore, we investigated from our results by means comparison with other methods and drawing 3D and 2D graph of the accurate obtained results

In this present essay, we test the efficiency of the popularized (