The aim of this study was to determine the use of paracetamol and ibuprofen combination for pain relief after oral surgery in children. Children under 10 years old having one or more wisdom teeth removed under general or local anesthesia were instructed to take two tablets before operation, then two tablets every 4 h for up to 36 h of a combination of acetaminophen 250 mg and ibuprofen 150 mg per tablet and acetaminophen 250 mg per tablet alone and ibuprofen 150 mg per tablet alone. The primary outcome measure was the area under the curve of the 100 mm visual analogue scale pain measurements taken for up to 36 h after surgery, divided by time, at rest and on activity. The result showed although all four secondary endpoints favor the combination treatment, only the global pain rating reached statistical significance. More participants experienced ‘nil’ or ‘mild’ pain with the combination (68.4%) than with either other group; this difference was significant for acetaminophen (37.5%; P=0.008), but not for ibuprofen (54.3%; P=0.263). The use of any rescue medication also favored the combination treatment, but this did not reach statistical significance. In conclusion, we could demonstrated that patients using the combination of acetaminophen and ibuprofen experienced less pain during the first 48 h after oral surgery than those using the same daily dosage of either agent alone and we think the difference was clinically relevant.

This study was to evaluate the effects of using peppermint, rosemary and savory on performance, carcass traits, some blood biochemical and immune parameters of heat stressed broiler chicks. A total of 200 day-old (male and female) Ross 308 broiler chicks were divided in four treatments and they were given to five replicates of 10 birds each. The treatments were the birds allocated in comfortable temperature and heat stress (34 ± 2 ˚C for 8 hours) with or without peppermint, rosemary and savory essences (0.2 ml/L) per each kg of diet respectively. The body weight (BW), feed intake (FI) and feed conversion ratio (FCR) were calculated. In the end of the trial carcass traits such as (dressing weight, breast, thigh, liver, heart, spleen and bursa of fabricus) were determined. The blood samples were collected and serum glucose content and blood plasma activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were measured. Additionally plasma IgG were quantified on days 21, 28, 35 and 42.Data from this study showed that the peppermint, rosemary and savory essences did not affect FI and FCR. The BW were increased with herbal inclusion (P≤0.05). As result revealed from this study the herbal could decrease the plasma glucose, AST and ALT of heat stressed broilers significantly (P≤0.05). The blood IgG of heat stressed broilers, increased with herbal essences utilization (P≤0.05). Briefly, it was concluded that using of 0.2 ml of herbals essences per kg diet may improve performance and better economic proficiency in broiler chicks. It was may be relative due to accumulation of minute advantages in greater WG, FI, and improved IG and lowered hepatic enzymes.

The study carried out is related to the synthesis of antibiotics, which are effective against the pathogenic bacteria using porous materials catalysts. Effective addition of amines to a series of α, β-unsaturated alkenes was performed by using the H-Clay catalyst to synthesize effective antibiotics in order to destroy or stop the growth of pathogenic bacteria. The operation was carried out in extremely appropriate conditions: ambient temperature, solvent-free, and green catalyst \"environmentally friendly», so the products that are synthesized give very high yields against pathogenic bacteria and excellent chemo-selectivity

Although v illage peace committees are playing a critical role in building and strengthening factors that fosters peace in ward 8 of Seke district of Masho they have quite notable downsides. The major one is naland east province, Zimbabwe, dependence upon individuals volunteering and serving but if volunteers are not forthcoming, or do little after joining the committee, they can fail both in the short and lo ng term. Another is i f a village composition of the peace committee will be predominantly male. is maledominated, the Albeit these grey areas, v peace committees bonds and embr are spearheading income generating activities acing the nonviolent resolution of conflict. This , encouraging illage associati onal form of local agency which is based on the ground conditions and interactions the villages. Key words: forms the basis for the sustaiming peace framework.

Agave americana is a species that is worth less because of the minimal effort exerted to make their cartographic profile. Here, we have exploited their applied potentialities through metabolic and biochemical abilities. In this case, we monitored the presence of terpenoides, phlobatanins, tannins, anthraquinone, puerarin, apigenin, carbohydrates and vitamin C. The proteins amount was estimated to be 8.13 mg/g. In addition, the enzymological characterization of A. americana leave juice consists of various enzymatic activities like protease (356 U.mL-1) and α-amylase (264 U.ml-1). The last (AmyAga) was purified after two purification steps, their optimal activity is showed at 70 °C and pH 9. Eventually, those findings indicate their potential use in baking industry in which AmyAga upgrades some parameter’s like elasticity index, baking strength, humidity and fall time. We note that vitamin C inhibitory capacity towards some enzymes such as glucosidases was 3 folds higher than those of exhibiting against amylases.

Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is the major enzyme assimilating CO2 into the biosphere. In this work, we report the extraction, the purification of the Alfalfa Rubisco. Indeed, the purification steps give birth to the purified Rubisco heterodimer composed of two subunits (13 and 55 kDa) as indicated in SDS-PAGE gel. In addition, the Rubisco proteolytic process (via protease-K) was optimized. The Box-Behnken Response Surface Methodology was applied to optimize three factors for increasing peptide production. These three independent parameters namely the protease-K concentration (6, 13, and 20 mg/mL), the reaction incubation time (6,8, and 10h) and the reaction temperature (30, 43, and 56°C) were selected for the experimental design. A best condition of a 20 mg/mL of protease-K, a 10 h of time incubation, and a 30°C of temperature treatment resulted in a 79.83%. This yield was 2.66 times higher than the one achieved before optimization. The resulting hydrolysate was injected in gel filtration column coupled to HPLC giving rise to four fractions (F1, F2, F3 and F4) eluted respectively after 12.54 min, 12.47 min, 12.44 min and 12.60 min. At the same time the ROS scavenging system was monitored like the CAT, SOD and also the DPPH capacity. Eventually, those findings will give birth to the opportunity to seek for plausible biotechnological investigations.